Dallas Buyers Club, directed by Canada’s Jean-Marc Vallée, earned acting trophies for Matthew McConaughey and Jared Leto at the Academy Awards on Sunday night.

The indie film from co-producer Voltage Pictures about HIV- positive cowboy-turned-alternative medicine activist Ron Woodroof also picked up an Oscar for best makeup and hairstyling.

McConaughey confirmed predictions to win the Oscar for best actor, and Leto, in the first prize-giving on the night in Los Angeles, grabbed the best supporting actor prize for his star-turn as an HIV-positive transgender prostitute.

Dallas Buyers Club, which is released in Canada by Remstar, missed out on Oscars for best original screenplay and film editing.

It was also a big night for the Montreal-based crew of The Lady in Number 6: Music Saved My Life, which was named best documentary short.

Directed by Montreal’s Malcolm Clarke and executive produced by Frederic Bohbot of Montreal-based Bunbury Films (in association with U.S.-based Reed Entertainment), the film tells the story of Holocaust survivor Alice Herz-Sommer, who passed away last week at the age of 110. Other Montreal-based talent on the film included editor Carl Freed, composer Luc St-Pierre and director of photography/co-producer Kieran Crilly.

Canadian nominees coming up short at the Oscars included Toronto composer Owen Pallett and Arcade Fire member Will Butler as their original score for Spike Jonze’s film Her lost out to the winning original score for Gravity, and Toronto sound producer Andy Koyama’s sound mixing for Lone Survivor also losing out to Gravity, Alfonso Cuarón’s sci-fi epic.

And Toronto-raised producer David Gerson and his nominated work Omar were beaten by Italy’s The Great Beauty in the best foreign language film competition.

with files from Katie Bailey