One of Canwest’s higher-profile U.S. pickups is now Global’s second miss of the fall season, with word that NBC has canned the Christian Slater-starrer My Own Worst Enemy.

The spy drama, in which Slater plays a man with two personalities, netted fair reviews but failed to build an audience after a promising debut on Oct. 13, when it garnered over half a million viewers in the Monday 10 p.m. timeslot. (All numbers 2+.) Enemy aired in simulcast, opposite CTV heavyhitter CSI: Miami and The Mentalist on A.

A Global spokesperson says the remaining four episodes of the series will air until the end of fall, with plans to announce its replacement once mid-season shows have been confirmed. In all, nine episodes will have aired on Global and NBC — where the show averaged around 5.9 million viewers, according to Variety.

Global also appears to have lost the romantic comedy The Ex-List, which was abruptly pulled from CBS’ schedule last month and is presumed axed. Cop drama Life has taken over its Friday 9 p.m. spot on Global.

Joining Enemy on the chopping block is NBC’s Lipstick Jungle, airing here on Rogers’ Citytv, which will bow out after the remaining episodes of its 13-ep second season have aired. The drama, about three high-powered friends, averaged less than 300,000 viewers Wednesdays at 10 p.m. on the five City stations from Sept. 1 to Oct. 19. No word from Rogers on what will replace the series.