It’s a new look CTV this fall as the broadcaster unveiled key scheduling changes to its primetime lineup at Thursday’s upfront presentation — in stark contrast to a 2009-10 sked that remained virtually unchanged from the year before.

CTV hopes to continue its winning streak with seven new series, including the buzzed-about The Conan O’Brien Show, while anchoring the schedule with returning hits such as Grey’s Anatomy, The Amazing Race and Dancing with the Stars.

‘We’ve altered significantly. The strategy was to use the stability of the core schedule and build around it… we wanted to throw a few surprises in the mix,’ SVP of program scheduling Mike Cosentino told Playback Daily prior to the network’s glitzy upfront party at Toronto’s Thompson Hotel.

The key scheduling changes involve the top-rated yet aging CSIs, with CSI: Miami moving to Sunday at 10 p.m. while CSI: New York settles into the Friday 9 p.m. slot – both in simulcast with CBS. Curiously, the original will air Thursdays at 7 p.m., a slot formerly held by Vampire Diaries, which moves to A.

‘It’s a challenge with shows that become older,’ admits Cosentino, though he maintains that the CSIs are still ‘performing programs’ and suggests the timeslot moves could help them find new viewers.

Further changes to the schedule involve dropping Access Hollywood at 7:30 p.m. and replacing it with comedy The Big Bang Theory, which Cosentino hopes will serve as a strong lead-in to the 8 p.m. hour.

Meanwhile, ABC’s Castle moves permanently from A to the main network, where it will air in the competitive Monday 10 p.m. slot opposite Global’s Hawaii Five-O and Citytv’s new Jerry Bruckheimer series Chase.

Tuesdays will see new U.S. pickup No Ordinary Family, about a family who discover they possess unique superpowers, go head-to-head with the sophomore season of Glee at 8 p.m.

Law & Order: Los Angeles joins the schedule Wednesdays at 10 p.m., preceded by Criminal Minds and the performance ep of So You Think You Can Dance Canada, the latter which will be replaced by new drama The Defendors — starring Jim Belushi and Jerry O’Connell as a pair of Las Vegas lawyers – when it wraps.

Also new to CTV is the William Shatner-starrer $#+! My Dad Says, based on the popular Twitter account of the same name, and cop drama Bluebloods with Tom Selleck. Conan will air weeknights at 1 a.m., though CTV plans to broadcast episodes earlier on The Comedy Network. Timeslot details are pending. The caster also picked up The Marilyn Denis Show, airing weekdays at 10 a.m.

Fresh midseason fare include the Criminal Minds spin off featuring Forest Whitaker, the Paula Abdul-produced reality competition Got to Dance, comedy Mr. Sunshine with Matthew Perry, and copro The Borgias.

CTV also confirmed it has ordered new seasons for Canuck series including Flashpoint, The Bridge, The Listener, Hiccups and Dan For Mayor.